| Round | Date | H/A | Brk Max | Brks Over 30 | W/L | Pts | v | Pts | Away | Team | Brks Over 30 | Brk Max |
| Week 1 | 30/09/2021 | Away | | | Lost | 81 | v | 83 | Beaton, James (-17) | The Grange | | |
| Week 2 | 07/10/2021 | Home | | | Lost | 46 | v | 73 | Aspinall, Wayne (11) | Eagle Sports | | |
| Week 6 | 04/11/2021 | Home | | | Lost | 71 | v | 73 | Ashley, Ray (29) | Penketh Cons 'B' | | |
| Week 8 | 18/11/2021 | Away | | | Lost | 80 | v | 86 | Brown, John (29) | Alford 'D' | | |
| Week 10 | 02/12/2021 | Away | | | Won | 76 | v | 41 | Barton, John (-1) | G.E.S.M. 'A' | | |
| Week 11 | 09/12/2021 | Home | | | Won | 85 | v | 47 | Daintith, Lee (15) | Kings Club 'C' | | |
| Week 12 | 16/12/2021 | Away | | | Won | 92 | v | 86 | Sweeney, Graham (37) | Bridgewater 'A' | | |
| Week 13 | 06/01/2022 | Home | | | Lost | 52 | v | 88 | Taylor, Alan (-2) | Irlam Catholic | | |
| Week 15 | 20/01/2022 | Away | | | Won | 78 | v | 67 | Sutcliffe, Tony (3) | Eagle Sports | | |
| Week 19 | 17/02/2022 | Away | | | Lost | 78 | v | 85 | Finney, James (27) | Penketh Cons 'B' | | |
| Week 22 | 10/03/2022 | Away | | | Won | 105 | v | 100 | Brown, Ryan (48) | Walkers 'B' | | |
| Week 23 | 17/03/2022 | Home | | | Won | 72 | v | 50 | Livingstone, Scott (4) | G.E.S.M. 'A' | | |
| Week 25 | 31/03/2022 | Home | | | Won | 87 | v | 76 | Thomason, Dennis (43) | Bridgewater 'A' | | |
| Week 26 | 21/04/2022 | Away | | | Lost | 49 | v | 82 | Ward, Dave (3) | Irlam Catholic | | |
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