| Round | Date | H/A | Brk Max | Brks Over 30 | W/L | Pts | v | Pts | Away | Team | Brks Over 30 | Brk Max |
| Week 3 | 14/10/2021 | Away | | | Lost | 37 | v | 78 | Taylor, Alan (-2) | Irlam Catholic | | |
| Week 4 | 21/10/2021 | Home | 48 | 1 | Won | 107 | v | 58 | Molyneux, Ian (40) | The Grange | | |
| Week 5 | 28/10/2021 | Away | | | Won | 66 | v | 55 | Aspinall, Wayne (11) | Eagle Sports | | |
| Week 7 | 11/11/2021 | Away | | | Lost | 76 | v | 78 | Tate, James (32) | Woolston 'A' | | |
| Week 8 | 18/11/2021 | Home | | | Won | 86 | v | 43 | McInerney, Martin (18) | Kings Club 'A' | | |
| Week 9 | 25/11/2021 | Away | | | Won | 73 | v | 70 | Ashley, Ray (29) | Penketh Cons 'B' | | |
| Week 10 | 02/12/2021 | Home | | | Lost | 41 | v | 76 | Dunst, Keith (36) | Irlam Steel | | |
| Week 12 | 16/12/2021 | Home | | | Won | 75 | v | 60 | Brown, Wes (16) | Walkers 'B' | | |
| Week 13 | 06/01/2022 | Home | | | Won | 74 | v | 51 | Delaney, Mike (15) | Monks 'A' | | |
| Week 14 | 13/01/2022 | Home | | | Won | 79 | v | 60 | Ormesher, Danny (29) | Kings Club 'C' | | |
| Week 15 | 20/01/2022 | Away | | | Won | 61 | v | 48 | Nesbitt, Paul (-11) | Bridgewater 'A' | | |
| Week 18 | 10/02/2022 | Home | 37 | 1 | Won | 76 | v | 37 | Manfredi, Renzo (16) | Eagle Sports | | |
| Week 20 | 24/02/2022 | Home | | | Won | 104 | v | 9 | Wilkinson, Mark (-6) | Woolston 'A' | | |
| Week 21 | 03/03/2022 | Away | | | Lost | 59 | v | 86 | Whittaker, Tyler (22) | Kings Club 'A' | | |
| Week 22 | 10/03/2022 | Home | | | Won | 54 | v | 47 | Giblin, James (-4) | Penketh Cons 'B' | | |
| Week 23 | 17/03/2022 | Away | 41 | 1 | Won | 80 | v | 50 | Doyle, Pat (17) | Irlam Steel | | |
| Week 24 | 24/03/2022 | Home | | | Lost | 29 | v | 87 | Morley, Matt (-4) | Alford 'D' | 1 | 35 |
| Week 25 | 31/03/2022 | Away | 35 | 1 | Lost | 55 | v | 69 | Bailey, Craig (26) | Walkers 'B' | | |
| Week 26 | 21/04/2022 | Away | | | Lost | 45 | v | 53 | Miller, Steve (16) | Monks 'A' | | |
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