| Round | Date | H/A | Brk Max | Brks Over 30 | W/L | Pts | v | Pts | Away | Team | Brks Over 30 | Brk Max |
| Week 1 | 30/09/2021 | Away | | | Won | 86 | v | 79 | Forster, Steven (44) | Woolston 'C' | | |
| Week 2 | 07/10/2021 | Home | | | Lost | 63 | v | 83 | Stephenson, Laurence (28) | Kings Club 'B' | | |
| Week 3 | 14/10/2021 | Away | | | Lost | 64 | v | 76 | Small, John (15) | Warrington Cons 'B' | | |
| Week 4 | 21/10/2021 | Home | | | Lost | 70 | v | 94 | Wilcock, Tony (41) | Penketh Cons 'A' | | |
| Week 5 | 28/10/2021 | Away | | | Lost | 73 | v | 97 | Brereton, Jason (12) | St Benedicts 'A' | | |
| Week 6 | 04/11/2021 | Home | | | Won | 86 | v | 80 | Mcnally, Neil (40) | Deaf Social 'A' | | |
| Week 7 | 11/11/2021 | Away | | | Won | 85 | v | 70 | Young, Gareth (37) | Deaf Social 'B' | | |
| Week 8 | 18/11/2021 | Home | | | Won | 82 | v | 57 | Jones, Russ (8) | Alford 'B' | | |
| Week 10 | 02/12/2021 | Home | | | Won | 73 | v | 37 | Brown, Scott (0286) (11) | Walkers 'A' | | |
| Week 11 | 09/12/2021 | Away | | | Lost | 58 | v | 90 | Carmichael, Angus (30) | The Hatter | | |
| Week 12 | 16/12/2021 | Home | | | Lost | 45 | v | 110 | Butler, Tony (18) | G.E.S.M. 'B' | | |
| Week 15 | 20/01/2022 | Away | | | Won | 111 | v | 80 | Farrar, Lee (30) | Kings Club 'B' | | |
| Week 16 | 27/01/2022 | Home | | | Lost | 59 | v | 69 | McNamee Jr, Danny (22) | Warrington Cons 'B' | | |
| Week 18 | 10/02/2022 | Home | | | Lost | 61 | v | 77 | Brereton, Jason (12) | St Benedicts 'A' | | |
| Week 19 | 17/02/2022 | Away | | | Won | 90 | v | 72 | Bryan, Mike (31) | Deaf Social 'A' | | |
| Week 20 | 24/02/2022 | Home | | | Lost | 91 | v | 95 | Morley, Peter (46) | Deaf Social 'B' | | |
| Week 21 | 03/03/2022 | Away | | | Won | 82 | v | 49 | Taylor, Chris (6) | Alford 'B' | | |
| Week 22 | 10/03/2022 | Home | | | Lost | 46 | v | 115 | Babington, Brian (25) | Alford 'A' | | |
| Week 24 | 24/03/2022 | Home | | | Lost | 50 | v | 89 | Malkin, Nick (12) | The Hatter | | |