| Round | Date | H/A | Brk Max | Brks Over 30 | W/L | Pts | v | Pts | Away | Team | Brks Over 30 | Brk Max |
| Week 1 | 30/09/2021 | Away | | | Lost | 61 | v | 82 | Charnock, Leon (34) | Walkers 'A' | | |
| Week 2 | 07/10/2021 | Home | | | Won | 79 | v | 62 | Brierley, Ollie (22) | G.E.S.M. 'B' | | |
| Week 3 | 14/10/2021 | Away | | | Lost | 77 | v | 78 | Scott, Ray (35) | Woolston 'C' | | |
| Week 4 | 21/10/2021 | Home | | | Lost | 52 | v | 100 | McNamee Snr, Danny (31) | Warrington Cons 'B' | | |
| Week 5 | 28/10/2021 | Home | | | Won | 79 | v | 78 | Broadfield, Peter (29) | Woolston 'B' | | |
| Week 6 | 04/11/2021 | Away | | | Lost | 44 | v | 103 | Johnson, Anthony (42) | Deaf Social 'B' | | |
| Week 7 | 11/11/2021 | Home | | | Lost | 63 | v | 84 | Babington, Brian (25) | Alford 'A' | | |
| Week 8 | 18/11/2021 | Away | | | Lost | 40 | v | 102 | Chisnall, Lee (22) | The Hatter | | |
| Week 12 | 16/12/2021 | Away | | | Lost | 49 | v | 88 | Lambert, Peter (28) | Deaf Social 'A' | | |
| Week 13 | 06/01/2022 | Home | | | Lost | 66 | v | 70 | Taylor, Chris (6) | Alford 'B' | | |
| Week 14 | 13/01/2022 | Home | | | Lost | 57 | v | 88 | Dixon, Carl (34) | Walkers 'A' | | |
| Week 15 | 20/01/2022 | Away | | | Won | 72 | v | 61 | Ford, Ste (18) | G.E.S.M. 'B' | | |
| Week 16 | 27/01/2022 | Home | | | Lost | 71 | v | 75 | Forster, Steven (44) | Woolston 'C' | | |
| Week 17 | 03/02/2022 | Away | | | Won | 98 | v | 60 | Lawton, Richard (36) | Warrington Cons 'B' | | |
| Week 18 | 10/02/2022 | Away | | | Lost | 68 | v | 95 | Bate, Ray (25) | Woolston 'B' | | |
| Week 19 | 17/02/2022 | Home | | | Lost | 74 | v | 98 | Wray, Paul (50) | Deaf Social 'B' | | |
| Week 20 | 24/02/2022 | Away | | | Lost | 69 | v | 91 | Babington, Louis (20) | Alford 'A' | | |
| Week 25 | 31/03/2022 | Home | | | Lost | 51 | v | 103 | Ward, Jonny (35) | Deaf Social 'A' | | |
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