| Round | Date | H/A | Brk Max | Brks Over 30 | W/L | Pts | v | Pts | Away | Team | Brks Over 30 | Brk Max |
| Week 5 | 28/10/2021 | Away | | | Won | 93 | v | 83 | Bonehill, Dave (43) | Woolston 'A' | | |
| Week 6 | 04/11/2021 | Home | | | Lost | 67 | v | 99 | Taylor, Scott (28) | Kings Club 'A' | | |
| Week 7 | 11/11/2021 | Away | | | Lost | 68 | v | 91 | Finney, James (27) | Penketh Cons 'B' | | |
| Week 8 | 18/11/2021 | Home | | | Won | 87 | v | 69 | Thorpe, Steve (30) | Irlam Steel | | |
| Week 9 | 25/11/2021 | Home | | | Lost | 64 | v | 74 | Delaney, Mike (15) | Monks 'A' | | |
| Week 10 | 02/12/2021 | Away | | | Lost | 66 | v | 98 | Brown, Terry (37) | Walkers 'B' | | |
| Week 12 | 16/12/2021 | Away | | | Lost | 53 | v | 88 | Corns, Les (0) | Kings Club 'C' | 1 | 44 |
| Week 13 | 06/01/2022 | Home | | | Lost | 90 | v | 102 | Sweeney, Graham (37) | Bridgewater 'A' | | |
| Week 19 | 17/02/2022 | Away | | | Won | 67 | v | 62 | McJay, Mitch (25) | Kings Club 'A' | | |
| Week 20 | 24/02/2022 | Home | | | Won | 87 | v | 75 | Herriot, Glen (25) | Penketh Cons 'B' | | |
| Week 21 | 03/03/2022 | Away | | | Lost | 53 | v | 86 | Owen, Mike (10) | Irlam Steel | | |
| Week 23 | 17/03/2022 | Home | | | Won | 90 | v | 80 | Bailey, Billy (43) | Walkers 'B' | | |
| Week 25 | 31/03/2022 | Home | | | Lost | 60 | v | 90 | Ormesher, Danny (29) | Kings Club 'C' | | |
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